Understanding the Dose-Dependent Hepatotoxicity of Diethyl Phthalate in Female Wistar Rats ๐๐ฌ
Diethyl Phthalate (DEP) is a ubiquitous plasticizer used in a staggering array of consumer products, from cosmetics and fragrances to medical devices and food packaging. While it enhances flexibility and longevity in plastics, its biological impact—specifically regarding liver health—has become a focal point of modern toxicological research. Recent studies focusing on the Dose-Dependent Hepatotoxicity of Diethyl Phthalate in Female Wistar Rats provide critical insights into how varying exposure levels can compromise hepatic integrity. For those leading the charge in this vital research, you can explore more at environmentalscientists.org to see how these findings shape environmental policy. The Mechanism of Liver Injury ๐งช The liver is the primary site for the metabolism of xenobiotics, making it highly susceptible to the toxic effects of phthalates. In female Wistar rats, the administration of DEP has been shown to trigger significant oxidative stress. As the dosage increases, the l...